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People at high risk of developing cervical, endometrial or breast cancer

breast cancerRisk factors are those that increase the likelihood that people exposed to them develop cancer. They can be dietary factors, professional, behavioral, endocrine, genetic, or drug related.

The identification of high-risk population groups based on these risk factors allows doing a cancer prophylaxis through both periodic clinical and laboratory controls, screening and through the treatment of precancerous conditions identified.

The breast cancer risk group

Age over 45 years; a breast lump is more common: an adenoma before 30 years or fibrocystic mastitis or cancer between 35 and menopause, cancer almost always at less than 2 years of menopause.

Hormonal factors: early puberty, late menopause as an expression of prolonged ovarian activity; the birth of the first child when older than 25 years, lack of breastfeeding, celibacy, nulliparity – are risk factors for breast cancer;

Familial predisposition is a major risk factor in women with first and second degree relatives who developed breast cancer (mother, sister, aunt).

Standard of living conditions predisposing to disease.

Diet high in fat, obesity.

A history of fibrocystic mastitis, ductal cancer in situ and lobular cancer in situ.

The cervical cancer risk group

Age – maximum frequency between 40-50 years, carcinoma in situ showing 10 years earlier;

There is a family predisposition for this cancer;

Lifestyle seems to have a role in the development of this cancer, which is found in women with early sexual activity and with multiple partners. It occurs frequently in prostitutes and almost never in virgins. It is more common in women with low socioeconomic level and from less developed countries.

Personal medical history is represented by common genital infections of parasitic and viral infections more often untreated: Trichomonas vaginalis, papillomavirus type A 16, 18, herpes virus type II. The presence of severe dysplasia (CIN III) can be identified in patients who will develop cancer if these lesions are not treated properly. The identification of dysplastic lesions, supervision and treatment are mandatory.

Risk group for cancer of the endometrium

Older age, most often after menopause, 60-70 years;

Hormonal factors are certainly involved in cancers of the endometrium because there of their presence of women in the following categories:

a) nulliparous

b) Having Stein-Leventhal syndrome

c) Prolonged administration of estrogen in postmenopausal women without progestin association

d) Early menarche, late menopause

Medical history:

a) Adenomatous hyperplasia of the endometrium which may be followed by the development of a carcinoma in situ and invasive cancer afterwards.

b) The triad of diabetes, hypertension, obesity is frequently observed in women who develop cancer of the endometrium.




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